Human T-lymphotropic type-1 virus specific antibody detected in sera of HIV/AIDS patients in Ghana.
Identifieur interne : 000F89 ( Main/Exploration ); précédent : 000F88; suivant : 000F90Human T-lymphotropic type-1 virus specific antibody detected in sera of HIV/AIDS patients in Ghana.
Auteurs : Andrew Anthony Adjei [Ghana] ; Theophilus Korku Adiku ; Patrick Ferdinand Ayeh Kumi ; Akosua Benefah DomfehSource :
- Japanese journal of infectious diseases [ 1344-6304 ] ; 2003.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Anticorps antiviraux (immunologie), Anticorps antiviraux (sang), Femelle, Ghana (épidémiologie), Humains, Infections opportunistes liées au SIDA (virologie), Infections à HTLV-I (), Infections à HTLV-I (immunologie), Infections à HTLV-I (épidémiologie), Mâle, Prévalence, Syndrome d'immunodéficience acquise (), Syndrome d'immunodéficience acquise (immunologie), Syndrome d'immunodéficience acquise (sang), Virus T-lymphotrope humain de type 1 (immunologie).
- MESH :
- immunologie : Anticorps antiviraux, Infections à HTLV-I, Syndrome d'immunodéficience acquise, Virus T-lymphotrope humain de type 1.
- sang : Anticorps antiviraux, Syndrome d'immunodéficience acquise.
- virologie : Infections opportunistes liées au SIDA.
- épidémiologie : Ghana, Infections à HTLV-I.
- Adulte, Adulte d'âge moyen, Femelle, Humains, Infections à HTLV-I, Mâle, Prévalence, Syndrome d'immunodéficience acquise.
- Wicri :
- geographic : Ghana.
English descriptors
- KwdEn :
- AIDS-Related Opportunistic Infections (virology), Acquired Immunodeficiency Syndrome (blood), Acquired Immunodeficiency Syndrome (complications), Acquired Immunodeficiency Syndrome (immunology), Adult, Antibodies, Viral (blood), Antibodies, Viral (immunology), Female, Ghana (epidemiology), HTLV-I Infections (complications), HTLV-I Infections (epidemiology), HTLV-I Infections (immunology), Human T-lymphotropic virus 1 (immunology), Humans, Male, Middle Aged, Prevalence.
- MESH :
- chemical , blood : Antibodies, Viral.
- geographic , epidemiology : Ghana.
- blood : Acquired Immunodeficiency Syndrome.
- complications : Acquired Immunodeficiency Syndrome, HTLV-I Infections.
- epidemiology : HTLV-I Infections.
- immunology : Acquired Immunodeficiency Syndrome, Antibodies, Viral, HTLV-I Infections, Human T-lymphotropic virus 1.
- virology : AIDS-Related Opportunistic Infections.
- Adult, Female, Humans, Male, Middle Aged, Prevalence.
Abstract
Serum samples from 124 acquired immunodeficiency syndrome (AIDS) hospitalized patients at the Fevers Unit, Korle-Bu Teaching Hospital, Accra, Ghana, were examined by the particle agglutination test for antibodies to human T-lymphotropic virus type 1 (HTLV-1) core proteins. The subjects included 84 males and 40 females, aged 16 to 54 years. Specific antibodies were detected in only 14 out of the 124 sera samples, giving an overall prevalence rate of 11.29%. The incidence was lower in males (5.95%; 5/84) than in females (22.50%; 9/40) (P<0.05). In both sexes, the age distribution of subjects positive for HTLV-1 antibodies ranged from 35 to 54 years. The prevalence rate reported herein is too low to suggest an association of HTLV-1 with AIDS, though it may indicate an opportunistic infection of AIDS patients by HTLV-1. Whether HTLV-1 is an underlying disease association or whether HTLV-1 plays some auxiliary role in the acquisition and progression of AIDS remains to be determined.
PubMed: 12824686
Affiliations:
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Le document en format XML
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<term>Acquired Immunodeficiency Syndrome (complications)</term>
<term>Acquired Immunodeficiency Syndrome (immunology)</term>
<term>Adult</term>
<term>Antibodies, Viral (blood)</term>
<term>Antibodies, Viral (immunology)</term>
<term>Female</term>
<term>Ghana (epidemiology)</term>
<term>HTLV-I Infections (complications)</term>
<term>HTLV-I Infections (epidemiology)</term>
<term>HTLV-I Infections (immunology)</term>
<term>Human T-lymphotropic virus 1 (immunology)</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Prevalence</term>
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<term>Adulte d'âge moyen</term>
<term>Anticorps antiviraux (immunologie)</term>
<term>Anticorps antiviraux (sang)</term>
<term>Femelle</term>
<term>Ghana (épidémiologie)</term>
<term>Humains</term>
<term>Infections opportunistes liées au SIDA (virologie)</term>
<term>Infections à HTLV-I ()</term>
<term>Infections à HTLV-I (immunologie)</term>
<term>Infections à HTLV-I (épidémiologie)</term>
<term>Mâle</term>
<term>Prévalence</term>
<term>Syndrome d'immunodéficience acquise ()</term>
<term>Syndrome d'immunodéficience acquise (immunologie)</term>
<term>Syndrome d'immunodéficience acquise (sang)</term>
<term>Virus T-lymphotrope humain de type 1 (immunologie)</term>
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<term>HTLV-I Infections</term>
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<term>Infections à HTLV-I</term>
<term>Syndrome d'immunodéficience acquise</term>
<term>Virus T-lymphotrope humain de type 1</term>
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<term>Human T-lymphotropic virus 1</term>
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<term>Syndrome d'immunodéficience acquise</term>
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<term>Femelle</term>
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<front><div type="abstract" xml:lang="en">Serum samples from 124 acquired immunodeficiency syndrome (AIDS) hospitalized patients at the Fevers Unit, Korle-Bu Teaching Hospital, Accra, Ghana, were examined by the particle agglutination test for antibodies to human T-lymphotropic virus type 1 (HTLV-1) core proteins. The subjects included 84 males and 40 females, aged 16 to 54 years. Specific antibodies were detected in only 14 out of the 124 sera samples, giving an overall prevalence rate of 11.29%. The incidence was lower in males (5.95%; 5/84) than in females (22.50%; 9/40) (P<0.05). In both sexes, the age distribution of subjects positive for HTLV-1 antibodies ranged from 35 to 54 years. The prevalence rate reported herein is too low to suggest an association of HTLV-1 with AIDS, though it may indicate an opportunistic infection of AIDS patients by HTLV-1. Whether HTLV-1 is an underlying disease association or whether HTLV-1 plays some auxiliary role in the acquisition and progression of AIDS remains to be determined.</div>
</front>
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<affiliations><list><country><li>Ghana</li>
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<region><li>Région du Grand Accra</li>
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<tree><noCountry><name sortKey="Adiku, Theophilus Korku" sort="Adiku, Theophilus Korku" uniqKey="Adiku T" first="Theophilus Korku" last="Adiku">Theophilus Korku Adiku</name>
<name sortKey="Domfeh, Akosua Benefah" sort="Domfeh, Akosua Benefah" uniqKey="Domfeh A" first="Akosua Benefah" last="Domfeh">Akosua Benefah Domfeh</name>
<name sortKey="Kumi, Patrick Ferdinand Ayeh" sort="Kumi, Patrick Ferdinand Ayeh" uniqKey="Kumi P" first="Patrick Ferdinand Ayeh" last="Kumi">Patrick Ferdinand Ayeh Kumi</name>
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<country name="Ghana"><region name="Région du Grand Accra"><name sortKey="Adjei, Andrew Anthony" sort="Adjei, Andrew Anthony" uniqKey="Adjei A" first="Andrew Anthony" last="Adjei">Andrew Anthony Adjei</name>
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